Targeted Chemotherapy
(Molecular pathway and angiogenesis inhibitors, vascular disrupters)
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Phase I Sunitinib and Gemcitabine in Treating Patients With Pancreatic Cancer or Other Solid Tumors
http://www.clinicaltrials.gov/ct2/show/NCT00462553?term=solid+tumor+immunology&recr=Open&age=12&rank
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Phase I E7389 and Gemcitabine in Treating Patients With Metastatic Solid Tumors or Solid Tumors That Cannot be Removed by Surgery
http://www.clinicaltrials.gov/ct2/show/NCT00410553?term=solid+tumor+immunology&recr=Open&age=12&rank
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Phase 1 Dose-Escalation PK/PD Trial in Advanced Cancer Patients
http://clinicaltrials.gov/ct2/show/NCT00610194?term=rdea119+AND+phase+i&rank=1
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Phase I Nelfinavir in Treating Patients With Metastatic, Refractory, or Recurrent Solid Tumors
http://tinyurl.com/5mrbc3
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Phase I Safety Study of IPI-504 in Patients With Gastrointestinal Stromal Tumors (GIST) or Soft Tissue Sarcomas (STS)
http://www.clinicaltrials.gov/ct2/show/NCT00276302?term=IPI-504&rank=1
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Phase I Study of XL647 Administered Orally Daily to Patients With Solid Tumors
http://www.clinicaltrials.gov/ct2/show/NCT00336765?term=solid+tumor&recr=Open&rank=194
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Phase I Drug Interaction Study of Sorafenib and Rapamycin in Advanced Malignancies
http://tinyurl.com/2vl3za
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Phase I Study of Oral PX-478 in Advanced Solid Tumors or Lymphoma
http://www.clinicaltrials.gov/ct/show/NCT00522652?order=1
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Phase I Study of the Safety and Pharmacokinetics of XL765 in Adults With Solid Tumors
http://tinyurl.com/34roxk
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Phase I Sorafenib and Temsirolimus in Treating Patients With Unresectable or Metastatic Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00255658?order=39
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Phase I Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00368914?order=12
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Phase I Imatinib Mesylate, Bevacizumab, and Cyclophosphamide in Treating Patients With Refractory Metastatic Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00390156?order=2
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Phase I Bevacizumab and Sunitinib in Treating Patients With Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00357318?order=2
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Phase I Study of PXD101 in Patients With Advanced Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00413075?order=1
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Phase I A Study To Test The Effect Of GW786034 (Pazopanib) On P450 Enzymes
http://www.clinicaltrials.gov/ct/show/NCT00401583?order=1
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Phase I A Two-Way Crossover Study Of The Effect Of Food On The Pharmacokinetics Of Pazopanib In Cancer Patients
http://www.clinicaltrials.gov/ct/show/NCT00363194?order=10
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Phase I Dose Escalation Study of ARQ 171 in Adult Patients With Advanced Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00398840?order=1
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Phase I/II Trial of Torisel and Liposomal Doxorubicin in Patients With Advanced Soft Tissue and Bone Sarcomas
http://www.clinicaltrials.gov/ct2/show/NCT00949325?term=leiomyosarcoma&rank=49
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Phase I/II RDEA119 and Sorafenib Combination Dose Escalation Study
http://clinicaltrials.gov/ct2/show/NCT00785226?term=rdea119+AND+phase+i&rank=2
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Phase I/II Study of MGCD0103 (MG-0103) in Combination With Gemcitabine
http://www.clinicaltrials.gov/ct/show/NCT00372437?order=2
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Phase I/II Safety and Efficacy Study Using Rexin-G for Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00505713?order=28
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Phase II Letrozole in Women With Advanced Estrogen/Progesterone Receptor Positive Uterine Leiomyosarcoma
http://www.clinicaltrials.gov/ct2/show/NCT00856050?term=leiomyosarcoma&rank=2
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Phase II A Five-Tier, Open-Label Study of IMC-A12 Administered as a Single Agent
http://tinyurl.com/6l7k4u
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Phase II Trial of Dasatinib in Advanced Sarcomas
http://www.clinicaltrials.gov/ct/show/NCT00464620?order=2
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Phase II A Study of LY573636-Sodium in the Treatment of Patients With Metastatic Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00490451?order=73
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Phase II Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas
http://www.clinicaltrials.gov/ct/show/NCT00474994?order=1
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Phase II Study of Sunitinib Malate for Metastatic and/or Surgically Unresectable Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00400569?order=1
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Phase II Trial of Cetuximab in Patients With Metastatic and/or Locally Advanced Soft Tissue and Bony Sarcomas
http://www.clinicaltrials.gov/ct/show/NCT00148109?order=45
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Phase II Letrozole Versus Observation in Patients With Newly Diagnosed Uterine Leiomyosarcoma
http://www.clinicaltrials.gov/ct/show/NCT00414076?order=1
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Phase II Study of Neoadjuvant Bevacizumab and Radiation Therapy for Resectable Soft Tissue Sarcomas
http://www.clinicaltrials.gov/ct/show/NCT00356031?order=12
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Phase II VEGF Trap in Treating Patients With Recurrent or Metastatic Gynecologic Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00390234?order=10
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Phase II Trabectedin in Treating Patients With Advanced, Persistent, or Recurrent Leiomyosarcoma of the Uterus
http://www.clinicaltrials.gov/ct/show/NCT00379145?order=17
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Phase II Trial of Cetuximab in Patients with Metastatic and/or Locally Advanced Soft Tissue and Bony Sarcomas
http://www.clinicaltrials.gov/ct/show/NCT00148109?order=64
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Phase III Randomized Double Blind Phase III Trial of Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy
http://www.clinicaltrials.gov/ct2/show/NCT00753688?term=Pazopanib+AND+sarcoma&rank=1
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Phase III Deforolimus (AP23573) in Treatment of Sarcoma - SUCCEED (Sarcoma Multi-Center Clinical Evaluation of the Efficacy of Deforolimus) Study
http://www.clinicaltrials.gov/ct/show/NCT00538239?order=1
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Phase III Study to Provide Access to Trabectedin in Patients With Soft Tissue Sarcoma Who Have Persistent or Recurrent Disease and Who Are Not Expected to Benefit From Currently Available Standard of Care Treatment
http://www.clinicaltrials.gov/ct/show/NCT00210665?order=1
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Cytotoxic Chemotherapy
(Kills all fast growing cells – healthy & cancerous)
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Phase I Sunitinib and Gemcitabine in Treating Patients With Pancreatic Cancer or Other Solid Tumors
http://www.clinicaltrials.gov/ct2/show/NCT00462553?term=solid+tumor+immunology&recr=Open&age=12&rank
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Phase I E7389 and Gemcitabine in Treating Patients With Metastatic Solid Tumors or Solid Tumors That Cannot be Removed by Surgery
http://www.clinicaltrials.gov/ct2/show/NCT00410553?term=solid+tumor+immunology&recr=Open&age=12&rank
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Phase I Gemcitabine and ON 01910.Na in Treating Patients With Advanced or Metastatic Solid Tumors
http://www.clinicaltrials.gov/ct2/show/NCT00822939?term=solid+tumor+immunology&recr=Open&age=12&rank
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Phase I PR-104 and Docetaxel or Gemcitabine in Treating Patients With Solid Tumors
http://www.clinicaltrials.gov/ct2/show/NCT00459836?term=solid+tumor+immunology&recr=Open&age=12&rank
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Phase I LBH589 and Gemcitabine in the Treatment of Solid Tumors
http://www.clinicaltrials.gov/ct2/show/NCT00550199
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Phase I Doxorubicin and Flavopiridol in Treating Patients With Metastatic or Recurrent Sarcoma That Cannot Be Removed By Surgery
http://www.clinicaltrials.gov/ct/show/NCT00098579?order=40
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Phase I Dose Evaluation Study Of Oral Eltrombopag In Patients With Sarcoma Receiving The ADRIAMYCIN And Ifosfamide Regimen
http://www.clinicaltrials.gov/ct/show/NCT00358540?order=55
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A Phase Ib Open-Label, Two-Arm, Dose-Finding Study of E7389 in Combination with Carboplatin in Patients with Solid Tumors (CHICAGO)
http://www.clinicaltrials.gov/ct/show/NCT00268905?order=1
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A Phase 1b/2 Study of AMG 655 in Combination With Doxorubicin for the First-Line Treatment of Unresectable Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct2/show/NCT00626704
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Phase I/II Trial of Torisel and Liposomal Doxorubicin in Patients With Advanced Soft Tissue and Bone Sarcomas
http://www.clinicaltrials.gov/ct2/show/NCT00949325?term=leiomyosarcoma&rank=49
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Phase I/II Dose-Escalation Study of TH-302 in Combination With Doxorubicin to Treat Patients With Advanced Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct2/show/NCT00742963?term=TH302&rank=1
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Phase I/II Study of Gemcitabine, Docetaxel and Bevacizumab in Patients With Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00276055?order=48
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Phase II Evaluation of Side Effects and Relative Activity of Two Chemotherapy Regimens in the Treatment Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00189137?order=50
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Phase II Palifermin in Patients With Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00267046?order=46
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Phase II Adjuvant Chemotherapy for High Risk Uterine Leiomyosarcoma
http://www.clinicaltrials.gov/ct/show/NCT00282087?order=2
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Immunotherapy
(Vaccines, viral or gene therapy)
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Phase 1 Study of BIIB022 (Anti-IGF-1R Monoclonal Antibody) in Relapsed/Refractory Solid Tumors
http://www.clinicaltrials.gov/ct2/show/NCT00555724?term=solid+tumor+immunology&recr=Open&age=12&rank
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Phase I Study of of MORAb-004 in Subjects With Solid Tumors
http://www.clinicaltrials.gov/ct2/show/NCT00847054?term=solid+tumor+immunology&recr=Open&age=12&rank
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Phase II Gene-Modified Lymphocytes, High-Dose Aldesleukin, and Vaccine Therapy in Treating Patients With Progressive or Recurrent Metastatic Cancer
http://www.clinicaltrials.gov/ct2/show/NCT00704938?term=solid+tumor+cancer+vaccine&recr=Open&rank=6
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Phase I Safety and Immune Response to a Multi-Component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer
http://www.clinicaltrials.gov/ct/show/NCT00423254?order=119
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Phase I One Time Injection of Bacteria to Treat Solid Tumors That Have Not Responded to Standard Therapy
http://clinicaltrials.gov/show/NCT00358397
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Phase II Safety and Efficacy Study of REOLYSIN(r) in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung
http://www.clinicaltrials.gov/ct/show/NCT00503295?order=9
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Interventional Radiology
(RFA, cryoablation, ultrasound, cyberknife)
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Phase II Cryotherapy and GM-CSF in Treating Patients With Lung Metastases or Primary Lung Cancer
http://www.clinicaltrials.gov/ct2/show/NCT00514215?term=solid+tumor+immunology&recr=Open&age=12&rank
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Phase III Radiation Therapy in Treating Patients Who Have Undergone Surgery for Soft Tissue Sarcoma of the Arms, Hands, Legs, or Feet
http://www.clinicaltrials.gov/ct2/show/NCT00423618?term=leiomyosarcoma&rank=52
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PET Scan Combined With CT Scan in Predicting Response in Patients Undergoing Chemotherapy and Surgery for Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct2/show/NCT00346125?term=leiomyosarcoma&rank=56
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Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg
http://www.clinicaltrials.gov/ct2/show/NCT00589121
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Cryotherapy in Treating Patients With Primary Lung Cancer or Lung Metastases
http://clinicaltrials.gov/show/NCT00303901
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Stem Cell
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Phase II Peripheral Stem Cell Transplant and White Blood Cell Transfusions in Treating Patients With Refractory Metastatic Solid Tumors
http://clinicaltrials.gov/ct/show/NCT00001880?order=1
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Phase II Stem Cell Transplantation for Metastatic Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00001880?order=84
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Combined Methods
(Chemo + radiation + surgery, etc.)
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Phase I Post-Operative Chemoradiation for Extremity & Trunk Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00502411?order=38
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Phase I Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery
http://www.clinicaltrials.gov/ct/show/NCT00450736?order=12
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Phase I/II PCI-24781 in Combination With Doxorubicin to Treat Sarcoma
http://clinicaltrials.gov/ct2/show/NCT01027910
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Phase I/II Monoclonal Antibody IMC-A12 and Doxorubicin in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct2/show/NCT00720174?term=leiomyosarcoma&rank=44
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A Phase I/II Study of MGCD0103 (MG-0103) in Combination With Gemcitabine
http://www.clinicaltrials.gov/ct/show/NCT00372437?order=14
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Phase I/II Hyperthermia, Radiation Therapy, Surgery, and Optional Chemotherapy in Treating Patients With Soft Tissue Sarcoma of the Limbs
http://www.clinicaltrials.gov/ct/show/NCT00093509?order=35
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Phase II Bevacizumab and Radiation Therapy for Sarcomas
http://www.clinicaltrials.gov/ct/show/NCT00356031?order=29
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Phase II External Beam Radiation With Intratumoral Injection Of Dendritic Cells As Neo-Adjuvant Treatment for Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00365872?order=37
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Other
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Collecting Tumor Samples From Patients With Gynecological Tumors (107 locations)
http://www.clinicaltrials.gov/ct2/show/study/NCT00897442?term=leiomyosarcoma&rank=62&show_locs=Y#loc
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The Exceptional Patient in Cancer Care
http://www.clinicaltrials.gov/ct/show/NCT00543153?order=42
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Molecular Profiling Protocol (SCRI-CA-001)
http://www.clinicaltrials.gov/ct/show/NCT00530192?order=1
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Stress Management Therapy in Patients Receiving Chemotherapy for Cancer
http://www.clinicaltrials.gov/ct/show/NCT00377130?order=1
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Biobank Sarcoma: Storing Blood for Analysis of DNA and Protein of Patients With Sarcoma (Netherlands)
http://www.clinicaltrials.gov/ct/show/NCT00181480?order=31
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PET Scan and CT Scan in Predicting Response in Patients Undergoing Chemotherapy and Surgery for Soft Tissue Sarcoma
http://tinyurl.com/sy4cc
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Phase I PET Scan Combined With CT Scan in Evaluating Treatment Response in Patients Undergoing Treatment for Bone Cancer or Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00335751?order=1
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Phase II Study of Sativex(R) for Pain Relief in Patients With Advanced Malignancy. (SPRAY)
http://www.clinicaltrials.gov/ct2/show/NCT00530764
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Phase II/III Ginger in Treating Nausea in Patients Receiving Chemotherapy for Cancer
http://www.clinicaltrials.gov/ct/show/NCT00040742?order=72
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Phase II/III Chemo Drug Sensitivity Microculture (MiCK) Assay for Apoptosis
http://www.clinicaltrials.gov/ct/show/NCT00243685?order=21
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Phase III Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
http://www.clinicaltrials.gov/ct2/show/NCT00538850?term=leiomyosarcoma&rank=73
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