Clinical Trials Available
for LMS or Solid Tumors (Outside the USA)


 

We are pleased to provide this space for you to list clinical trials open to leiomyosarcoma patients.   For complete listings search at www.clinicaltrials.gov
Please send us new or updated information.  (
See disclaimer)

 


Trials are listed by type:

Targeted Chemotherapy    (Pathway and angiogenesis inhibitors, vascular disrupters)
Cytotoxic Chemotherapy    (Kills fast growing healthy & cancerous cells)
Immunotherapy    (Vaccines, viral or gene therapy)
Interventional Radiology    (RFA, cryoablation, ultrasound, cyberknife)
Stem Cell   
Combined Methods    (Chemo + radiation + surgery)
Other   

Targeted Chemotherapy
(Molecular pathway and angiogenesis inhibitors, vascular disrupters)


Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid Tumours (Canada)
http://www.clinicaltrials.gov/ct2/show/NCT00566410?term=Dichloroacetate&rank=1


Phase I SB939 in Treating Patients With Locally Advanced or Metastatic Solid Tumors (Canada)
http://www.clinicaltrials.gov/ct/show/NCT00504296?order=100


Phase I Study of PXD101 in Patients With Advanced Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00413075?order=1


A Phase I Study of PXD101 Alone and in Combination With 5-FU in Patients With Advanced Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00413322?order=2


Phase I Study of BMS-354825 in Patients With Solid Tumors
http://www.clinicaltrials.gov/ct/show/NCT00339144?order=17


Phase II Brostallicin or Doxorubicin as First-Line Therapy in Treating Patients With Relapsed, Refractory, or Metastatic Soft Tissue Sarcoma (Netherlands)
http://clinicaltrials.gov/show/NCT00410462


Phase II BAY-43-9006 in Advanced, Metastatic Soft Tissue Sarcomas (Italy)
http://www.clinicaltrials.gov/ct/show/NCT00406601?order=61


Phase II Pemetrexed in Patients With Soft Tissue Sarcoma (Germany)
http://www.clinicaltrials.gov/ct/show/NCT00427466?order=48


Phase II VEGF Trap in Treating Patients With Recurrent or Metastatic Gynecologic Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00390234?order=10


Phase III Deforolimus (AP23573) in Treatment of Sarcoma - SUCCEED (Sarcoma Multi-Center Clinical Evaluation of the Efficacy of Deforolimus) Study
http://www.clinicaltrials.gov/ct/show/NCT00538239?order=1

Cytotoxic Chemotherapy
(Kills all fast growing cells – healthy & cancerous)


Phase I E7389 and Gemcitabine in Treating Patients With Metastatic Solid Tumors or Solid Tumors That Cannot be Removed by Surgery
http://www.clinicaltrials.gov/ct/show/NCT00410553?order=2


Phase I and II Trial With TLC D-99 and Ifosfamide in Metastatic Soft Tissue Sarcoma Patients
http://www.clinicaltrials.gov/ct/show/NCT00289809?order=91


Phase II Pemetrexed in Patients With Soft Tissue Sarcoma (Germany)
http://www.clinicaltrials.gov/ct/show/NCT00427466?order=40


Phase II Study of E7389 in Patients With Advanced and/or Metastatic Soft Tissue Sarcoma
http://www.cancer.gov/clinicaltrials/EORTC-62052


Phase II Trofosfamide Versus Adriamycin in Elderly Patients With Soft Tissue Sarcoma (STS)
http://www.clinicaltrials.gov/ct/show/NCT00204568?order=52


Phase II Study of Vinorelbine + Cyclofosfamide Among Patients With Refractory Tumors or in Relapse
http://www.clinicaltrials.gov/ct/show/NCT00180947?order=82


Phase II Gemcitabine With or Without Docetaxel as Second-Line Therapy in Treating Patients With Metastatic or Relapsed, Unresectable Uterine or Soft Tissue Leiomyosarcoma
http://www.clinicaltrials.gov/ct/show/NCT00227669?order=1


Phase III Randomized Phase 3 Non Metastatic Uterine Sarcomas
http://www.clinicaltrials.gov/ct/show/NCT00162721?order=76


Phase III Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00061984?order=6

Immunotherapy
(Vaccines, viral or gene therapy)


Phase I/II Allogeneic Tumor Cell Vaccination in Patients With Solid Tumors (Israel)
http://www.clinicaltrials.gov/ct/show/NCT00148993?order=4


Phase II Cell Therapy of Cancer With Allogeneic Blood Lymphocytes Activated With rIL-2 for Metastatic Solid Tumors (Israel)
http://www.clinicaltrials.gov/ct/show/NCT00149006?order=10


Phase II Treatment of Patients With Donor Lymphocytes Sensitized by Antigens Expressed by the Host (Israel)
http://www.clinicaltrials.gov/ct/show/NCT00149032?order=12


Phase II A Novel Vaccine for the Treatment of MUC1-Expressing Tumor Malignancies (Israel)
http://www.clinicaltrials.gov/ct/show/NCT00162500?order=8

Interventional Radiology
(RFA, cryoablation, ultrasound, cyberknife)


Phase II IMRT Lower Limb Soft Tissue Sarcoma
http://www.clinicaltrials.gov/ct/show/NCT00188175?order=59

Stem Cell



Combined Methods
(Chemo + radiation + surgery, etc.)


Phase I-II Trial of Sorafenib in Combination With Ifosfamide in SoftTissue Sarcoma (Spain)
http://www.clinicaltrials.gov/ct/show/NCT00541840?order=205


Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Soft Tissue Sarcomas in First Line of Treatment for the Metastatic Disease (NGR011) (Italy)
http://www.clinicaltrials.gov/ct/show/NCT00484341?order=67

Other


The Exceptional Patient in Cancer Care
http://www.clinicaltrials.gov/ct/show/NCT00543153?order=42


An Adequate Cost Effective Follow Up Protocol For Bone & Soft Tissue Sarcomas - A Prospective Randomized Trial (India)
http://www.clinicaltrials.gov/ct/show/NCT00384735?order=79


Biobank Sarcoma: Storing Blood for Analysis of DNA and Protein of Patients With Sarcoma (Netherlands)
http://www.clinicaltrials.gov/ct/show/NCT00181480?order=31



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Last Edited - 16 October 2006 07:36 am